ppm 4.0 (bundled with ActivePerl 5.8.8 build 818 and 819) doesn't support post-install scripts to install external libraries by default (in the GUI mode), and ppm 4.01 bundled with build 820 seems a bit unstable for the post-installer. See ActivePerl's release notes for details.
If you use it in the CUI mode (namely type 'ppm install (package-name).ppd' at the command prompt), it seems to handle them, though poorly right now.
So, watch out when you install packages that use external libraries like openssl or libxml2 (or packages that depends on such packages), notably Plagger.
You might encounter segfaults with alert dialog saying something is missing. That's probably because ppm failed to install external libraries properly (or the libraries I offer may have been compiled with inadequate options). If this should happen, grab necessary libraries from somewhere including:
Or, check GnuWin32 libraries.
Other notable reason of segfaults is that you have incompatible versions of the libraries elsewhere with higher priority, such as c:\WINNT directory or c:\WINNT\System32. If you really know what you're going to do, you might want to replace the libraries. However, it might cause unexpected errors somewhere else. If you do, do at your own risk.